Aiptasia is a genus of a symbiotic cniarian belonging to the class Anthozoa (sea anemones, corals). Other well known cnidarian groups include the jellyfish (Class Scyphozoa), the hydroids (fire coral, and the genus Hydra), and the box jellyfish (Class Cubozoa). Aiptasia is widely distributed tropical sea anemone of benthic lifestyle typically found living on mangrove roots and nearby hard substrates. Interestingly, this anemone as well as many other cnidarian species is found to contain symbiotic dinoflagellate unicellular algae of the genus Symbiodinium living inside nutritive cells. The symbionts provide food mainly in the form of lipids and sugars produced from photosynthesis to the host while the hosts provides inorganic nutrients and a constant and protective environment to the algae. Species of Aiptasia are relatively weedy anemones able to withstand a relatively wide range of salinities and other water quality conditions. In the case of A. pallida and A. pulchella, their hardiness coupled with their ability to reproduce very quickly and out-compete other species in culture gives these anemones the status of pest from the perspective of coral reef aquarium hobbyists. Ironically, these characteristics make it easy to grow in the laboratory and thus it is extensively used as model system for scientific study. In this respect, Aiptasia has contributed a significant amount of knowledge regarding cnidarian biology, especially our understanding of cnidarian-algal symbioses, a biological phenomenon crucial to the survival of corals and coral reef ecosystems. The dependence of coral reefs on the health of the symbiosis is dramatically illustrated by the devastating effects experienced by corals due to the loss of algal symbionts in response to environmental stress, a phenomenon known as coral bleaching.