Caseous necrosis escribes a form of biological tissue death, caseous meaning it has a cheese-like appearance. The dead tissue appears as a soft and white proteinaceous dead cell mass. In caseous necrosis no histological architecture is preserved. On microscopic examination with H&E staining, it is characterized by acellular pink areas of necrosis surrounded by a granulomatous inflammatory process. Frequently, caseous necrosis is associated with tuberculosis (TB).