Chelionium majus, commonly known as the greater celandine or tetterwort (in America, the latter refers to Sanguinaria canadensis), is the only species in the genus Chelidonium, family Papaveraceae. The lesser celandine is not closely related, but its family, the Ranunculaceae, is allied to the Papaveraceae (Order Ranunculales). It is native to Europe and the Mediterranean basin. It is also widespread in North America, having been brought there by settlers as a herbal remedy for skin problems such as warts as early as 1672.