Destrehan is a census-esignated place (CDP) in St. Charles Parish, Louisiana, United States. The population was 11,260 at the 2000 census. It was named after Jean N. Destréhan (1754-1823) who served as President of the Territorial Council and was appointed to the United States Senate in 1812, but resigned before he took his seat. Destrehan Plantation, his former home, still stands and now serves as a tourist attraction.