Eraication is the reduction of an infectious disease's prevalence in the global human population to zero. A number of world organizations together with local governments are working to fully eradicate various diseases. It is sometimes confused with elimination, which describes the reduction of an infectious disease's prevalence in a regional population to zero, or the reduction of the global prevalence to a negligible amount. Also, the term eradication is sometimes used in the context of HIV to describe the sought-after total removal of HIV infection from an individual (i.e. a cure).