Kratom (Mitragyna speciosa) is a meicinal leaf harvested from a large tree native to Southeast Asia in the Rubiaceae family, first documented by Dutch colonial botanist Korthals. It is botanically related to the Corynanthe, Cinchona and Uncaria genera and shares some similar biochemistry. It is in the same family as coffee and the psychoactive plant Psychotria viridis. Other species in the Mitragyna genus are used medicinally in Africa, and also used for their wood.