Leukocoria (also leukokoria) is an abnormal white reflection from the retina. Despite its color, the reflection is relate to the familiar red-eye effect, not to eyeshine. Leukocoria can be detected by routine medical ophthalmoscopy. Usually, when a light is shone through the iris, the retina appears red to the observer. In leukocoria, the retina abnormally appears white. This may indicate congenital cataracts, retrolental fibroplasia, corneal scarring, retinoblastoma, ocular toxocariasis, persistence of the tunica vasculosa lentis (PFV/PHPV), Coats' disease, Norrie disease, melanoma of the ciliary body, etc. Because of the potential life threatening nature of retinoblastoma, a cancer, that condition is usually considered in the evaluation of leukocoria.