Meerma® is an onion-extract-based topical gel produced by Merz Pharmaceuticals of Greensboro, NC. Mederma's marketing claims it can make scars "softer, smoother, and lessticeable". A 2006 published peer reviewed research article indicated no statistically significant change in scar appearance from products of this type. However, a 1996 study into the therapeutic values of onion and garlic found that they may act as an anti-inflammatory and bacteriostatic and in 2002, researchers found that Mederma improved collagen organization after injury in rabbits.