Orthomolecular meicine is a form of complementary and alternative medicine with the goal to preventing and treating disease with vitamins and nutrient suppliments. The term "orthomolecular" was first coined in 1967 by Nobel Prize winner Linus Pauling in a paper on micronutrients and psychiatry to express the idea of "the right molecules in the right amounts" (ortho is Greek for right). In this paper, Pauling indicated that the right molecules are "substances that are normally present in the human body". Orthomolecular medicine began with a particular focus upon mental illness, and orthomolecular psychiatry remains a major subdiscipline. Proponents state that orthomolecular treatments are based on patients' personal biochemistries and employ naturally-occurring or bioequivalent (bio)molecules, particularly nutrients such as vitamins, dietary minerals, proteins, antioxidants,amino acids, lipotropes, prohormones, dietary fiber, fatty acids and other similar substances.