Trauma Center: Uner the Knife (超執刀 カドゥケウス, Chōshittō Kadukeusu?, lit. "Super Surgical Operation: Caduceus") is a surgical simulation game developed for the Nintendo DS and the first in the Trauma Center series. The game was remade for the Wii, titled Trauma Center: Second Opinion, and has spawned a sequel, Trauma Center: Under the Knife 2.